Cape Girardeau, Missouri Restaurant Closures and Closed Restaurants

Welcome to Cape Girardeau, Missouri, a charming city with a population of 47,054 nestled along the Mississippi River. Known for its stunning riverfront and vibrant community, Cape Girardeau has seen its fair share of culinary establishments come and go. This page highlights closed-down restaurants in the area, including those that have permanently closed, temporarily closed, or shut down for various reasons. Explore the legacy of dining in our beloved city, and remember the flavors that once graced our tables.

Disclaimer: The information on this website is provided as a resource, but it may not always be 100% accurate. While we strive to research and verify details, errors can occur, and businesses frequently change names, locations, or reopen after closing. Addresses, operating status, and other details may be outdated or incorrect. Use this information at your own risk. If you spot an error, please contact us here, and we will do our best to update it promptly.


Love old restaurant stories, local history, and keeping up with the places that quietly disappear? Our free weekday emails follow restaurant closures across the entire United States—one region at a time— with short stories, links, and context you won’t see in a headline. Sign up once, and you’ll get a quick tour of what closed this week, Monday through Friday.

    • 🌵 Southwest StoriesMonday
      Texas · New Mexico · Arizona · Oklahoma
    • 🌾 Midwest FarewellTuesday
      Iowa · Illinois · Indiana · Ohio · Michigan · Minnesota · Wisconsin · Missouri · Kansas · Nebraska · North Dakota · South Dakota
    • 🌤 Southern Last CallWednesday
      Louisiana · Mississippi · Alabama · Georgia · Florida · South Carolina · North Carolina · Tennessee · Kentucky · West Virginia · Arkansas
    • 🌊 Coastline ClosingsThursday
      California · Oregon · Washington · Alaska · Hawaii
    • 🏔 Mountain West ReportFriday
      Idaho · Montana · Wyoming · Colorado · Utah · Nevada
    • 🍁 New England NotesSaturday
      Maine · Vermont · New Hampshire · Massachusetts · Rhode Island · Connecticut
    • 🏙 Mid-Atlantic MemoSunday Morning
      New York · New Jersey · Pennsylvania · Delaware · Maryland · Washington, D.C.
Gabriel’s Food + Wine – Cape Girardeau – 127 Main St
127 Main St
Cape Girardeau, MO 63701
Status: Closed permanently
Baristas Coffee Bar – Cape Girardeau – 338 Broadway St
338 Broadway St
Cape Girardeau, MO 63701
Status: Closed permanently
Billiard Center – Cape Girardeau – 26 Main St
26 Main St
Cape Girardeau, MO 63701
Status: Closed permanently
Subway – Cape Girardeau – 3439 William St
3439 William St
Cape Girardeau, MO 63703
Status: Closed permanently
Gordonville Grill – Cape Girardeau – 829 State Hwy Z
829 State Hwy Z
Cape Girardeau, MO 63701
Status: Closed permanently
Cafe & Me – Cape Girardeau – 820 N Sprigg St #5
820 N Sprigg St #5
Cape Girardeau, MO 63701
Status: Closed permanently
Ruby Tuesday – Cape Girardeau – 3069 William St
3069 William St
Cape Girardeau, MO 63701
Status: Closed permanently
BG’s Deli – Cape Girardeau – 205 S Plaza Way
205 S Plaza Way
Cape Girardeau, MO 63703
Status: Closed permanently
Little Kitchen
1036 N Sprigg St
Cape Girardeau, MO 63701
Status: Permanently Closed

After 30 years in business, Little Cottage Café in Bismarck has closed. Owners Bob and Wanda cited health concerns and have personally repurchased unused gift certificates. Locals praised the restaurant’s integrity and community spirit.

Howard Johnson’s Restaurant – Cape Girardeau
I-55 & State Road K
Cape Girardeau, MO 63701
Status: Closed Permanently

Howard Johnson's Restaurant was located at I-55 & State Road K, Cape Girardeau, MO 63701.

Little Kitchen
1036 N Sprigg St
Cape Girardeau, MO
Status: Closed Down

Closing Nov. 15 after 10 years; Zia’s Indian Cuisine taking over.